Category Archives: CROI

  1. Reformulation of Tenofovir Vaginal Gel Safe for Rectal Use

    via A change in the formulation of tenofovir gel, an anti-HIV gel developed for vaginal use, may make it safer to use in the rectum, suggests a study published online this week in the Journal of Antimicrobial Chemotherapy. In laboratory tests of rectal tissue, researchers from the Microbicide Trials Network (MTN) found that the reformulated gel Read More >>

    2012, CROI, Microbicide Trials Network, Microbicides, MTN, MTN 007, rectal microbicide, Tenofovir, vaginal microbicide
  2. Researchers Present the Impact of Serosorting as an HIV Prevention Strategy

    via, by Gus Cairns An meta-analysis of HIV-negative gay men’s sexual behaviour and HIV incidence rate in four HIV prevention studies, presented earlier this month at the 19th Conference on Retroviruses and Opportunistic Infections (CROI), has found that attempting to ‘serosort’ by restricting unprotected sex to partners known to be HIV negative does have efficacy as Read More >>

    CROI, gay men, HIV, MSM, prevention, seroadaptation, serosorting
  3. NYT: Setback on PrEP Results May Have Been Misunderstood

    via The New York Times, by Donald G. McNeil Jr. The failure of a daily pill to protect healthy African women against AIDS may not have been the pill’s fault but the women’s reluctance to take it, scientists at an important AIDS conference in Seattle were told this week. Last April, a promising trial of “pre-exposure prophylaxis” Read More >>

    2012, clinical trials, CROI, pre-exposure prophylaxis, PrEP, Tenofovir, Truvada
  4. HIV/AIDS Treatments Compromised by Budget Cuts

    via Nature News, by Erika Check Hayden Preventing the spread of HIV used to mean testing people for infection and encouraging them to practise safe sex. Increasingly, it also means prescribing drugs, as studies show that giving infected people or their uninfected partners antiretroviral drugs as soon as an infection is diagnosed can help to check the Read More >>

    CROI, funding, HIV/AIDS, PEPFAR, President Barack Obama, Treatment, Treatment as Prevention, USA
  5. Researchers at CROI 2012 Share First Trial Results on Injectable HIV Drug Used as Prevention

    via, by Gus Cairns The first trial in humans of an injectable, once-a-month formulation of an HIV drug has found that drug levels were maintained at a level that should in theory be high enough to protect recipients against infection, and that the drug has so far produced very few side effects. The research was presented Read More >>

    clinical trials, CROI, HIV, injection drug use, Microbicide Trials Network, MTN, research
  6. Two Studies Show the Importance of Adherence in PrEP at CROI 2012

    via, by Gus Cairnes Adherence makes all the difference to the efficacy of pre-exposure prophylaxis (PrEP), the 19th Conference on Retroviruses and Opportunistic Infections (CROI) heard today. Further data were presented from two trials of PrEP (giving anti-HIV drugs to HIV-negative people to prevent infection), which announced dramatically different results last year. In April 2011, the Read More >>

    CROI, FEM-PrEP, HIV/AIDS. pre-exposure prophylaxis, Partners PrEP, pre-exposure prophylaxis, PrEP, Tenofovir, Truvada
  7. CROI 2012: iPrEx Researchers Test Dosage of PrEP

    via, by Gus Cairns Further testing of drug levels in the blood and immune cells of gay men participating in the iPrEx trial of tenofovir/FTC (Truvada) pre-exposure prophylaxis (PrEP) has found that HIV infection in men assigned to Truvada was associated with a lapse in taking the drug after initially adhering reasonably well, rather than never Read More >>

    CROI, iPrEx, PrEP, Tenofovir, Treatment, Truvada
  8. CROI Reports Rectal Tenofovir Trial Results

    via, by Gus Cairns A gel containing 1% tenofovir formulated specifically for rectal use was much better tolerated than gels used in previous rectal microbicide trials when used in a safety study in 65 HIV-negative men and women, the 19th Conference on Retroviruses and Opportunistic Infections (CROI) heard yesterday. The gel was also compared with other Read More >>

    clinical trials, CROI, Microbicide Trials Network, Microbicides, MTN 007, rectal microbicide, Tenofovir
  9. CROI 2012: Recent Results Presented by Partners PrEP Study

    via MedPage Today, by Michael Smith Giving anti-retroviral drugs to HIV-negative people can reduce their risk of acquiring the virus from an HIV-positive partner, a researcher said here. In a large randomized controlled trial in Africa, this type of pre-exposure prophylaxis, or PrEP, cut the risk of infection by up to 75% compared with placebo, according to Read More >>

    ARV, ARVs, CROI, HPTN052, Partners PrEP, PrEP
  10. Is treatment really reducing infections?

    via Aidsmap, by Gus Cairns Moupali Das of the San Francisco Department of Public Health presented evidence to show that the city’s intensive testing and treatment policy was beginning to result in a declining HIV infection rate there. Similar evidence was presented from the province of British Columbia in Canada. The evidence presented still leaves some questions Read More >>

    CROI, HIV, HIV/AIDS policy, TLC+, Treatment, viral load