Category Archives: Microbicide Trials Network

  1. AIDSmeds: Rectal Microbicide Shows Better Safety in Laboratory Study

    via AIDSmeds Laboratory testing of a modified version of the Viread (tenofovir) microbicide gel provides further evidence that it may be safe for rectal use, according to a paper published online ahead of print by the Journal of Antimicrobial Chemotherapy. The encouraging results contribute to a better understanding of the gel’s tolerability, already evident in preliminary findings Read More >>

    Microbicide Trials Network, MTN 007, MTN 017, rectal microbicide, research, Tenofovir, Truvada
  2. Reformulation of Tenofovir Vaginal Gel Safe for Rectal Use

    via Eurekalert.org A change in the formulation of tenofovir gel, an anti-HIV gel developed for vaginal use, may make it safer to use in the rectum, suggests a study published online this week in the Journal of Antimicrobial Chemotherapy. In laboratory tests of rectal tissue, researchers from the Microbicide Trials Network (MTN) found that the reformulated gel Read More >>

    2012, CROI, Microbicide Trials Network, Microbicides, MTN, MTN 007, rectal microbicide, Tenofovir, vaginal microbicide
  3. [VIDEO] McGowan and Pickett Talk the Rectal Microbicide Walk at Microbicides 2012

    Rectal microbicides were ALL OVER the Microbicides 2012 conference… Chatting up rectal microbicide research and advocacy activities and issues at the recent Microbicides 2012 conference (held in Sydney this past April) were Dr. Ian McGowan, co-principal investigator of the Microbicide Trials Network (and IRMA Scientific Co-Chair) and IRMA Chair Jim Pickett. Have a look/listen to their discussion Read More >>

    advocacy, Dr. Ian McGowan, IRMA, Jim Pickett, M2012, Microbicide Trials Network, Microbicides 2012, rectal microbicide, research, Sydney, video
  4. Researchers at CROI 2012 Share First Trial Results on Injectable HIV Drug Used as Prevention

    via AidsMap.com, by Gus Cairns The first trial in humans of an injectable, once-a-month formulation of an HIV drug has found that drug levels were maintained at a level that should in theory be high enough to protect recipients against infection, and that the drug has so far produced very few side effects. The research was presented Read More >>

    clinical trials, CROI, HIV, injection drug use, Microbicide Trials Network, MTN, research
  5. CROI Reports Rectal Tenofovir Trial Results

    via AidsMap.com, by Gus Cairns A gel containing 1% tenofovir formulated specifically for rectal use was much better tolerated than gels used in previous rectal microbicide trials when used in a safety study in 65 HIV-negative men and women, the 19th Conference on Retroviruses and Opportunistic Infections (CROI) heard yesterday. The gel was also compared with other Read More >>

    clinical trials, CROI, Microbicide Trials Network, Microbicides, MTN 007, rectal microbicide, Tenofovir
  6. Project ARM – Africa for Rectal Microbicides – Strategy Meeting a Success!

    Originally published by IRMA colleagues at Mapping Pathways here. “It was an amazing group, and one that moved me to near tears on a number of occasions”IRMA chairman Jim Pickett just returned from an inspiring week in Addis Ababa, Ethiopia, where he led a strategy meeting for the  IRMA’s Project ARM – Africa for Rectal Microbicides – and then attended Read More >>

    Africa, Dr. Ian McGowan, Ethiopia, Global Forum on MSM, Jim Pickett, lgbt community, Microbicide Trials Network, Microbicides, Project ARM, rectal microbicide
  7. IRMA Statement on Discontinuation of Gel Arm in VOICE Prevention Trial

    25 November, 2011IRMA Expresses Disappointment; Calls for MTN 017 to Move Forward International Rectal Microbicide Advocates (IRMA) expresses disappointment regarding today’s announcement that the vaginal tenofovir gel arm in the Microbicide Trial Network’s (MTN) VOICE trial is being discontinued. VOICE has been exploring two ARV-based HIV prevention approaches since it began enrolling women in high incidence areas Read More >>

    Microbicide Trials Network, MTN, MTN 017, rectal microbicide, Tenofovir, vaginal microbicide, VOICE
  8. First combination ARV vaginal ring for HIV prevention being tested in Phase I safety trial

    via EurekAlert In the first clinical trial of a vaginal ring combining two antiretroviral (ARV) drugs, researchers from the Microbicide Trials Network (MTN) are collaborating with the International Partnership for Microbicides (IPM) to evaluate whether the ring is safe for use in women. If the ring does prove to be safe, it could be considered for further Read More >>

    ARVs, Microbicide Trials Network, Microbicides, United States, vaginal microbicide
  9. Closure of oral Tenofovir arm in VOICE Pre-Exposure Prophylaxis trial: PrEP as a “niche intervention”?

    via Incidence, by Roger J. Tatoud The Microbicides Trial Network (MTN) September 28th that its VOICE (Vaginal and Oral Interventions to Control the Epidemic, MTN003) HIV Pre-Exposure Prophylaxis (PrEP) prevention study will discontinue the daily oral tenofovir arm of the trial. The decision follows an interim review of the trial’s data by its Data Safety and Monitoring Board Read More >>

    FEM-PrEP, Microbicide Trials Network, Microbicides, PrEP, TDF2
  10. Microbicide Trials Network Statement on Decision to Discontinue Use of Oral Tenofovir Tablets in VOICE, a Major HIV Prevention Study in Women

    via Microbicide Trials Network VOICE, an HIV prevention trial evaluating two antiretroviral (ARV)-based approaches for preventing the sexual transmission of HIV in women – daily use of one of two different ARV tablets or of a vaginal gel – will be dropping one of the oral tablets from the study. The decision to discontinue use of tenofovir Read More >>

    Africa, Microbicide Trials Network, PrEP, South Africa, Tenofovir, Truvada, Uganda, women, Zimbabwe